First 2020 collaborative article on RfaH fold switch now on Biophysical Journal!
Happy New Year, everybody! The article by awesome members Pablo Galaz-Davison and Alejo Molina, PhD students in Science in Engineering, was recently published in Biophysical Journal. In this article, we combined confinement molecular dynamics simulations and hydrogen-deuterium exchange mass spectrometry experiments to decipher which local regions are responsible of controlling the fold switch of RfaH, a bacterial antitermination factor responsible for expression of genes involved in bacterial virulence. This work was possible due to our long-standing collaboration with the laboratories of the amazing Irina Artsimovitch (Ohio State University) and the marvelous Elizabeth A. Komives (University of California San Diego), and a new collaboration with Stefan H. Knauer (Bayreuth University).
Congratulations, Pablo and Alejo, for a wonderful start of year 2020!