Happy New Year, everybody! The article by awesome members Pablo Galaz-Davison and Alejo Molina, PhD students in Science in Engineering, was recently published in Biophysical Journal. In this article, we combined confinement molecular dynamics simulations and hydrogen-deuterium exchange mass spectrometry experiments to decipher which local regions are responsible of controlling Read more…
Our fruitful collaboration with the group of Prof. Eduardo Agosin (Pontificia Universidad Católica de Chile) has been published in Food Chemistry. In this article, led by CONICYT postdoctoral fellow Nicole Werner, we engineered a carotene cleavage dioxygenase to optimize its tethering to the membrane. The goal was to increase the Read more…
Our new article in collaboration with Jorge Babul from Universidad de Chile has been published in Scientific Reports. In this article, we employed a combination of experiments a simulations to demonstrate that a non-conserved histidine residue enables pH-dependent modulation of the folding and dimerization stability of FoxP. HOORAY!
This is the list of publications from the PB3 Lab (since 2016) and from the PI during his PhD and position as researcher and independent researcher (before 2016). 2020 Galaz-Davison P, Molina JA, Silletti S, Komives EA, Knauer SH, Artsimovitch I* & Ramírez-Sarmiento CA*. (2020) Differential local stability governs the metamorphic Read more…